The invention discloses a method for realizing cross-border data synchronization based on domestic and overseas data centers. The method includes the following steps: setting a local server database in a local server; setting a target server database on a target server; selecting a server as the transfer server in the territory, and setting a transfer server database in the transfer server, wherein the local server is arranged in the territory and the target server is arranged outside the country; when the data of the local server database changes, generating a data change amount file, and setting a flag in the data change amount file, wherein the marking adopts the local server time. The method for realizing cross-border data synchronization of domestic and overseas data centers, by setting the above steps, after the communication transmission is interrupted and recovered, enables the overseas data to be synchronized quickly, thereby reducing the customs clearance risk and the customsclearance time, and reducing the overstock of packages.