The invention discloses a radiation enhanced transfusion interface automatic connecting device. The radiation enhanced transfusion interface automatic connecting device comprises an operating platform, a hydraulic press, a fixing plate and a first motor; the hydraulic press is arranged on the upper part of the operating platform; a first motor is arranged on the upper part of the hydraulic press;a driving rod is arranged on the upper part of the first motor; the driving rod is welded and fixed with a rotor of the first motor; and a driving shaft is arranged on the upper part of the driving rod. According to the radiation enhanced transfusion interface automatic connecting device, a mounting head moves into a second fixing groove, a magnetic ring in the mounting head is contacted with a first butting device, the first butting device is taken down and moves to a second fixing groove, a clamping groove in the first butting device is clamped and jogged with a second butting device, a second motor starts to drive the magnetic ring to rotate and the clamping block and the clamping groove are in threaded connection and fixation, so that automatic butting of the first butting device and the second butting device is realized, manual operation is not needed and medical staff is prevented from contacting with a radiation area again.