The embodiment of the invention relates to the technical field of automobiles, and discloses a man-machine interaction method and system based on a vehicle and the vehicle. The method comprises the following steps that whether the vehicle meets requirements of a first state entering a simulated experience mode is detected when the vehicle is in a showing mode; if the vehicle meets the requirementsof the first state entering the simulated experience mode, whether a user state meets the second state entering the simulated experience mode is detected; if the user state meets the second state entering the simulated experience mode, the simulated experience mode is started, and guide information is output in the simulated experience mode so as to guide a user to make a simulation action simulating fatigue driving or distracting driving; and in the simulated experience mode, a reminding content corresponding to a fatigue safety driving reminding function or a distracting driving reminding function of the vehicle is output if it is detected that the user makes the simulation action. According to the embodiment of the invention, the user can be quickly familiar with the safe driving reminding function of the vehicle, so that the occurrence rate of traffic accidents is reduced.