The invention discloses a non-radiative percutaneous spine positioning method based on optical scanning automated outline segmentation matching. Through a clinical image data processing system, clinical CT (computed tomography) is imported, a three-dimensional model of the back outline and the spine of a human body can be reconstructed, and a three-dimensional model of the back outline of the human body is scanned, checked and reconstructed through structured light/ TOF (Time Of Flight) optical scanning equipment, finally, a three-dimensional coordinate relationship between the spine model andthe optical scanning model of the back outline of the human body is displayed and output through the matching calculation of a three-dimensional image processing system. On the basis of optical scanning equipment, the method disclosed by the invention realizes the matching and the positioning of the spine model and the optical scanning model of the back outline of the human body, and has the advantages of no radiation, small land occupation, high scanning speed, visual display results, high repeatability and the like.