The invention provides an antenna structure. The antenna structure comprises a metal frame, a feeding source and a grounding point, wherein a first breakage point, a second breakage point, a first coupling part, a second coupling part and a radiation part are arranged on the metal frame, and the feeding source is electrically connected to the radiation part so as to feed a current signal to the radiation part; after the current is fed into the radiation part from the feeding source, the current can pass through the radiation part and is coupled to the first coupling part and the second coupling part, so that the radiation part, the first coupling part and the second coupling part are used for respectively stimulating and providing a first mode, a second mode and a third mode to generate radiation signals of a first frequency band, a second frequency band and a third frequency band; and after the current is fed into the radiation part from the feeding source, the current is coupled to the second coupling part and passes through a first end and a second end of the second coupling part to form a loop current. The invention also provides a wireless communication device with the antennastructure.