The present application discloses a method in which a base station transmits a reference signal sequence in a wireless communication system. In detail, the method comprises the steps of: generating a pseudo-random sequence using a first m-sequence and a second m-sequence; generating the reference signal sequence using the pseudo-random sequence; and transmitting the reference signal to a mobile station via antenna ports different from one another. The second m-sequence has an initial value containing parameters for discriminating reference signal sequences among users.