Invention Grant
- Patent Title: Method of generating ions of high mass to charge ratio by charge reduction
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Application No.: US15129128Application Date: 2015-03-24
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Publication No.: US10043646B2Publication Date: 2018-08-07
- Inventor: Jeffery Mark Brown , Jonathan Paul Williams
- Applicant: Micromass UK Limited
- Applicant Address: GB Wilmslow
- Assignee: MICROMASS UK LIMITED
- Current Assignee: MICROMASS UK LIMITED
- Current Assignee Address: GB Wilmslow
- Agency: Womble Bond Dickinson (US) LLP
- Agent Deborah M. Vernon; Heath T. Misley
- Priority: EP14161312 20140324; GB1405216.1 20140324; GB1405661.8 20140328
- International Application: PCT/GB2015/050860 WO 20150324
- International Announcement: WO2015/145124 WO 20151001
- Main IPC: H01J49/00
- IPC: H01J49/00

Abstract:
A method of charge stripping analyte ions is disclosed. The method comprises reacting the analyte ions with reagent ions or charged particles; and then urging the reacted analyte ions through a neutral, inert gas such that said analyte ions interact or collide with the gas molecules in a manner that reduces the charge state of the reacted analyte ions, thereby forming product ions of reduced charge state. The combination of reacting the analyte ions and then urging the reacted ions through the gas results in a charge reduction that is greater than that which would be caused by either of the individual steps of reacting the ions or urging the ions through the gas.
Public/Granted literature
- US20170125225A1 Method of Generating Ions of High Mass to Charge Ratio by Charge Reduction Public/Granted day:2017-05-04
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