Invention Grant
- Patent Title: Fusion protein comprising albumin and retinol-binding protein
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Application No.: US15615099Application Date: 2017-06-06
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Publication No.: US10064915B2Publication Date: 2018-09-04
- Inventor: Jun Seo Oh
- Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Applicant Address: KR Seoul
- Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Current Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: Ladas & Parry LLP
- Agent Loren K. Thompson
- Priority: KR10-2011-0018074 20110228
- Main IPC: C07K14/76
- IPC: C07K14/76 ; A61K38/17 ; A61K38/38 ; C07K14/765 ; C07K14/47

Abstract:
There is provided a fusion protein comprising albumin and retinol-binding protein (RBP), which can be used for preventing or treating fibrotic diseases. The fusion protein, in which albumin and RBP are bound together, is incorporated into stellate cells and induces phenotypic reversion from myofibroblast-like cells to quiescent fat-storing phenotype. Therefore, the fusion protein can be effectively used in preventing or treating fibrotic diseases occurring in the liver, pancreas, lung, or other organs.
Public/Granted literature
- US20170274044A1 FUSION PROTEIN COMPRISING ALBUMIN AND RETINOL-BINDING PROTEIN Public/Granted day:2017-09-28
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