In accordance with various embodiments, a method for uplink multiple accessing based on code division multiple access (CDMA) technology and a related system are provided. The method comprises: designing a practical uplink spreading waveform for a code division multiple access (CDMA) based SCN by leveraging a plurality of pseudorandom sequences and investigating a channel coding block and a modulation block for the CDMA based SCN; determining an uplink frequency sub-band division for the CDMA based SCN to optimize a tradeoff between a performance and an implementation cost of CDMA based SCN; and specifying a configuration of a control system of the CDMA based SCN.