- Patent Title: Uses of cyclic peptides for treating and preventing atherosclerosis
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Application No.: US14781859Application Date: 2014-04-02
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Publication No.: US10092620B2Publication Date: 2018-10-09
- Inventor: M. Reza Ghadiri , Luke J. Leman , Yannan Zhao , Bruce E. Maryanoff
- Applicant: THE SCRIPPS RESEARCH INSTITUTE
- Applicant Address: US CA La Jolla
- Assignee: The Scripps Research Institute
- Current Assignee: The Scripps Research Institute
- Current Assignee Address: US CA La Jolla
- Agent Hugh Wang; Thomas Fitting
- International Application: PCT/US2014/032620 WO 20140402
- International Announcement: WO2014/165563 WO 20141009
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/12
Abstract:
The present invention provides cyclic compounds that are useful in preventing or treating atherosclerosis or related disorders. The invention also provides therapeutic methods for treating or preventing various diseases or disorders associated with or mediated by atherosclerosis. Further provided in the invention are methods of screening for anti-atherosclerotic cyclic peptides with improved properties.
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