This disclosure is directed to a multiple input cryptographic engine. In general, an cryptographic engine consistent with the present disclosure may improve on existing systems that generate encrypted data (e.g., ciphertext) from decrypted input data (e.g., plaintext), or that conversely generate decrypted data from encrypted data, in that a second input may be received into the cryptographic engine while a first input is still being processed, allowing multiple inputs to be processed concurrently. An example device may include an input interface to receive data into the device, an output interface to output data from the device and cryptographic circuitry. The cryptographic circuitry may be configured encrypt/decrypt data received via the input interface into encrypted/decrypted data while also converting a least a portion of a second input received via the input interface into second encrypted/decrypted data. The encrypted/decrypted data may then be output via the output interface.