Invention Grant
- Patent Title: Microfluidic glycan analysis
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Application No.: US14664709Application Date: 2015-03-20
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Publication No.: US10209259B2Publication Date: 2019-02-19
- Inventor: Magdalena Anna Ostrowski , Rudolf Grimm , Kevin P. Killeen , Karla M. Robotti
- Applicant: Agilent Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee Address: US CA Santa Clara
- Main IPC: B01L3/00
- IPC: B01L3/00 ; G01N33/00 ; G01N33/68 ; F16K99/00 ; G01N27/447 ; G01N30/46 ; G01N30/60 ; G01N30/72 ; B01D15/08 ; G01N1/40 ; G01N30/08 ; H01J49/00
Abstract:
Microfluidic devices and methods for analyzing glycan profiles of glycoproteins are provided. Some embodiments of the devices comprise a deglycosylation column for cleaving glycans, an optional cleaning column for removing proteins, a trapping column for enriching glycans, and a separation column for resolving glycans. The devices and methods significantly improve the speed and sensitivity of glycan analysis.
Public/Granted literature
- US20150198611A1 Microfluidic Glycan Analysis Public/Granted day:2015-07-16
Information query
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