Invention Grant
- Patent Title: Compositions comprising CH505 envelopes, and trimers
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Application No.: US15513539Application Date: 2015-09-25
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Publication No.: US10232034B2Publication Date: 2019-03-19
- Inventor: Barton F. Haynes , Hua-Xin Liao , Bette T. Korber , Peter T. Hraber
- Applicant: Duke University , Los Alamos National Security, LLC
- Applicant Address: US NC Durham US NM Los Alamos
- Assignee: DUKE UNIVERSITY,LOS ALAMOS NATIONAL SECURITY, LLC
- Current Assignee: DUKE UNIVERSITY,LOS ALAMOS NATIONAL SECURITY, LLC
- Current Assignee Address: US NC Durham US NM Los Alamos
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- International Application: PCT/US2015/052346 WO 20150925
- International Announcement: WO2016/049522 WO 20160331
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K14/005 ; A61K39/12 ; A61K39/21 ; C12N7/00 ; A61K31/4706 ; A61K39/395 ; A61K47/48 ; C07K14/705
Abstract:
In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogens comprise an immune modulating component.
Public/Granted literature
- US20170281749A1 COMPOSITIONS COMPRISING CH505 ENVELOPES, AND TRIMERS Public/Granted day:2017-10-05
Information query
