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    Active stabilization of coherent controllers using nearby qubits
    3.
    发明授权
    Active stabilization of coherent controllers using nearby qubits 有权

    公开(公告)号：US12288132B2

    公开(公告)日：2025-04-29

    申请号：US17362810

    申请日：2021-06-29

    Applicant: University of Maryland, College Park ,  Duke University

    Inventor： Jungsang Kim ,  Kenneth Brown ,  Christopher Monroe

    IPC: G06N10/40

    Abstract: Aspects of the present disclosure describe techniques that involve an active stabilization of coherent controllers using nearby qubits. In an aspect, a quantum information processing (QIP) system for stabilizing phase damping in qubits is described that provides a first and a second qubit ion, measuring magnetic field fluctuations using the second qubit ion, and generates one or more magnetic fields based on the measured magnetic field fluctuations, the one or more magnetic fields being applied near the first qubit ion to cancel the magnetic field fluctuations to stabilize the phase damping of the first qubit ion. Another such QIP system performs provides a first and a second qubit ion, locks a local oscillator to a frequency reference associated with the second qubit ion, and tracks, using the local oscillator, a frequency of the first qubit ion based on the frequency reference. Methods associated with these QIP systems are also described.

    Re-imaging microscopy with micro-camera array
    5.
    发明授权
    Re-imaging microscopy with micro-camera array 有权

    公开(公告)号：US12259541B2

    公开(公告)日：2025-03-25

    申请号：US17675538

    申请日：2022-02-18

    Applicant: DUKE UNIVERSITY

    Inventor： Xi Yang ,  Pavan Chandra Konda ,  Roarke Horstmeyer

    IPC: G02B21/36 ,  H04N23/45

    Abstract: A microscopy system includes a primary lens and a planar array of micro-cameras. Each micro-camera of the planar array of micro-cameras has a field of view at an intermediate plane that overlaps at least one other micro-camera's field of view at the intermediate plane in a direction. The primary lens is disposed in a light path between the array of micro-cameras and a target area. In some cases, an overlap amount in the direction of the field of view at the intermediate plane for each micro-camera is at least 50%. A method of microscopy imaging includes directing light to a target area and simultaneously capturing a first set of images of the target area while the light illuminates the target area via a planar array of micro-cameras having a field of view at an intermediate plane disposed between a primary lens and the planar array of micro-cameras.

    COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS
    7.
    发明申请
    COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS 有权

    公开(公告)号：US20250052763A1

    公开(公告)日：2025-02-13

    申请号：US18718238

    申请日：2022-12-14

    Applicant: Duke University

    Inventor： Hiroaki Matsunami ,  Aashutosh Vihani

    IPC: G01N33/68 ,  G16B15/30 ,  G16B35/00

    Abstract: The present invention relates to compositions and methods for identifying odorant-odorant receptor interactions. In particular, the present invention relates to methods for identifying odorant receptor-odorant interactions based on odorant receptor amino acid sequence and other properties of odorant receptors and odorants. The methods provide, in part, for the broad surveying of OR responses, using an in vivo strategy, against a diverse panel of 10 odorants, followed by using the resulting interaction profiles to uncover relationships between OR responses, odorants, odor molecular properties, and OR sequences.

    Nano-plasmonic molecular probes and methods of use
    10.
    发明授权
    Nano-plasmonic molecular probes and methods of use 有权

    公开(公告)号：US12173355B2

    公开(公告)日：2024-12-24

    申请号：US16809674

    申请日：2020-03-05

    Applicant: Duke University

    Inventor： Tuan Vo-Dinh ,  Hsin-Neng Wang ,  Andrew Fales

    IPC: C12Q1/68 ,  A61K31/713 ,  C12Q1/6825

    Abstract: Plasmonics-active nanoprobes are provided for detection of target biomolecules including nucleic acids, proteins, and small molecules. The nucleic acids that can be detected include RNA, DNA, mRNA, microRNA, and small nucleotide polymorphisms (SNPs). The nanoproprobes can be used in vito in sensitive detection methods for diagnosis of diseases and disorders including cancer. Multiplexing can be performed using the nanoprobes such that multiple targets can be detected simultaneously in a single sample. The methods of use of the nanoprobes include detection by a visible color change. The nanoprobes can be used in vivo for treatment of undesireable cells in a subject.

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