Invention Grant
- Patent Title: Blockers of the growth hormone receptor in disease prevention and treatment
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Application No.: US14913130Application Date: 2016-02-12
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Publication No.: US10246446B2Publication Date: 2019-04-02
- Inventor: Valter D. Longo , Priya Balasubramanian , Nouri Neamati , Min Wei
- Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
- Applicant Address: US CA Los Angeles
- Assignee: University of Southern California
- Current Assignee: University of Southern California
- Current Assignee Address: US CA Los Angeles
- Agency: Brooks Kushman P.C.
- International Application: PCT/US2016/017717 WO 20160212
- International Announcement: WO2016/130901 WO 20160818
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D405/14 ; A61K31/55 ; A61K31/422 ; A61K31/4155 ; C07D413/12 ; A61K45/06 ; A61K31/4245 ; C07D405/06 ; C07D307/68 ; C07K16/26 ; C07K16/28 ; A61P25/00 ; A61P35/00 ; A61P25/28 ; A61K39/00

Abstract:
Compounds and methods for treating diseases or conditions affected by the activity or expression of genes/proteins related to human GH, GHR, STAT5, SOCS, IGF-1, insulin are provided. Monoclonal antibodies for treating diseases or conditions related to growth hormone and growth hormone receptor activity are also provided.
Public/Granted literature
- US20170342063A1 BLOCKERS OF THE GROWTH HORMONE RECEPTOR IN DISEASE PREVENTION AND TREATMENT Public/Granted day:2017-11-30
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