Invention Grant
- Patent Title: Reduction of oxidated methionine peptides for mass spectrometry
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Application No.: US15360662Application Date: 2016-11-23
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Publication No.: US10266866B2Publication Date: 2019-04-23
- Inventor: Michael Sweredoski , Annie Moradian , Tanya R. Yakushi , Sonja Hess , Roxana Eggleston-Rangel
- Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Lewis Roca Rothgerber Christie LLP
- Main IPC: C12P7/00
- IPC: C12P7/00 ; C12P21/02 ; C12N9/02 ; C12N11/08
Abstract:
A method for preparing a methionine containing peptide or protein for analysis by mass spectrometry by incubating the methionine containing peptide or protein with a heterologous methionine sulfoxide reductase A (MsrA), a heterologous methionine sulfoxide reductase B (MsrB), or a heterologous methionine sulfoxide reductase AB (MsrAB) enzyme results in the reduction of an oxidized methionine containing peptide or protein.
Public/Granted literature
- US20170152541A1 REDUCTION OF OXIDATED METHIONINE PEPTIDES FOR MASS SPECTROMETRY Public/Granted day:2017-06-01
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