Invention Grant
![Substituted imidazo[1,2-a]pyrazines as luciferase substrates](/docs/US/2019-06-04/US10308975B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted imidazo[1,2-a]pyrazines as luciferase substrates
-
Application No.: US15887735Application Date: 2018-02-02
-
Publication No.: US10308975B2Publication Date: 2019-06-04
- Inventor: Anton Shakhmin , Thomas Kirkland , Joel Walker , Thomas Machleidt , Mary Hall , Keith V. Wood
- Applicant: PROMEGA CORPORATION
- Applicant Address: US WI Madison
- Assignee: Promega Corporation
- Current Assignee: Promega Corporation
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones, S.C.
- Agent Anne M. Reynolds
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C12Q1/66 ; C07D519/00 ; A61K49/00 ; G01N33/58 ; H04N1/60
![Substituted imidazo[1,2-a]pyrazines as luciferase substrates](/abs-image/US/2019/06/04/US10308975B2/abs.jpg.150x150.jpg)
Abstract:
Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogs, kits comprising the compounds, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods for making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.
Public/Granted literature
- US20180223330A1 COELENTERAZINE ANALOGUES Public/Granted day:2018-08-09
Information query
