Invention Grant
- Patent Title: Polymer conjugates having reduced antigenicity and methods of using the same
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Application No.: US15387536Application Date: 2016-12-21
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Publication No.: US10364451B2Publication Date: 2019-07-30
- Inventor: Ashutosh Chilkoti , Yizhi Qi , Michael S. Hershfield , Nancy J. Ganson
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N9/96 ; A61K47/60 ; A61K47/58
Abstract:
Disclosed herein are compositions and methods for reducing the antigenicity of molecules. The antigenicity of a molecule may be reduced or eliminated by conjugating at least one branched polymer to the molecule to form a molecule-polymer conjugate. The branched polymer may include a backbone and a plurality of side chains, each side chain covalently attached to the backbone.
Public/Granted literature
- US20170239363A1 POLYMER CONJUGATES HAVING REDUCED ANTIGENICITY AND METHODS OF USING THE SAME Public/Granted day:2017-08-24
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