Invention Grant
- Patent Title: Cross-scale modeling of bioreactor cultures using Raman spectroscopy
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Application No.: US15322560Application Date: 2015-07-02
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Publication No.: US10563163B2Publication Date: 2020-02-18
- Inventor: Brandon Berry , Justin Moretto
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2015/039011 WO 20150702
- International Announcement: WO2016/004322 WO 20160107
- Main IPC: C12M1/34
- IPC: C12M1/34 ; C12M1/36 ; G01N21/65
Abstract:
Aspect of the disclosure relate to methods of assessing a bioreactor culture that involve determining a culture parameter of the manufacturing-scale bioreactor culture using a model that relates a Raman spectrum to the culture parameter. Related bioreactor system are also provided.
Public/Granted literature
- US20170355947A9 CROSS-SCALE MODELING OF BIOREACTOR CULTURES USING RAMAN SPECTROSCOPY Public/Granted day:2017-12-14
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