Systems and methods for non-blocking implementation of cache flush instructions are disclosed. As a part of a method, data is accessed that is received in a write-back data holding buffer from a cache flushing operation, the data is flagged with a processor identifier and a serialization flag, and responsive to the flagging, the cache is notified that the cache flush is completed. Subsequent to the notifying, access is provided to data then present in the write-back data holding buffer to determine if data then present in the write-back data holding buffer is flagged.