Invention Grant
- Patent Title: Anti-transthyretin antibodies
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Application No.: US16129618Application Date: 2018-09-12
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Publication No.: US10669330B2Publication Date: 2020-06-02
- Inventor: Yue Liu , Tarlochan S. Nijjar , Avijit Chakrabartty , Jeffrey N. Higaki
- Applicant: PROTHENA BIOSCIENCES LIMITED , UNIVERSITY HEALTH NETWORK
- Applicant Address: IE Dublin CA Toronto
- Assignee: PROTHENA BIOSCIENCES LIMITED,UNIVERSITY HEALTH NETWORK
- Current Assignee: PROTHENA BIOSCIENCES LIMITED,UNIVERSITY HEALTH NETWORK
- Current Assignee Address: IE Dublin CA Toronto
- Agency: Alston & Bird LLP
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K51/10 ; A61K39/00

Abstract:
The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
Public/Granted literature
- US20190071491A1 ANTI-TRANSTHYRETIN ANTIBODIES Public/Granted day:2019-03-07
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