Invention Grant
![Substituted imidazo[1,2-a]pyrazines as luciferase substrates](/docs/US/2020-06-02/US10669568B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted imidazo[1,2-a]pyrazines as luciferase substrates
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Application No.: US16390382Application Date: 2019-04-22
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Publication No.: US10669568B2Publication Date: 2020-06-02
- Inventor: Anton Shakhmin , Thomas Kirkland , Joel Walker , Thomas Machleidt , Mary Hall , Keith V. Wood
- Applicant: PROMEGA CORPORATION
- Applicant Address: US WI Madison
- Assignee: PROMEGA CORPORATION
- Current Assignee: PROMEGA CORPORATION
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones, S.C.
- Agent Anne M. Reynolds
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C12Q1/66 ; C07D519/00 ; A61K49/00 ; G01N33/58 ; H04N1/60
![Substituted imidazo[1,2-a]pyrazines as luciferase substrates](/abs-image/US/2020/06/02/US10669568B2/abs.jpg.150x150.jpg)
Abstract:
Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogues, kits comprising the compounds, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods from making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.
Public/Granted literature
- US20190241932A1 COELENTERAZINE ANALOGUES Public/Granted day:2019-08-08
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