Invention Grant
- Patent Title: Carbazole derivatives
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Application No.: US16289878Application Date: 2019-04-10
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Publication No.: US10676434B2Publication Date: 2020-06-09
- Inventor: Saleem Ahmad , Douglas G. Batt , Qingjie Liu , John E. Macor , Joseph A. Tino , Scott Hunter Watterson , Satheesh Kesavan Nair , Tarun Kumar Maishal
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D403/04 ; C07D209/88 ; A61K31/4523 ; C07D471/04 ; A61K31/403 ; C07D401/06 ; C07D403/06 ; C07D403/12 ; C07D471/10 ; C07D487/04 ; C07D495/04

Abstract:
Disclosed are compounds of Formula (I): or a salt thereof, wherein Q, R1a, R1b, R2a, R2b, R3, R4, R5a, R5b, R6a, R6c, R7a, R7b, R7c, and R7d are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Public/Granted literature
- US20190225583A1 CARBAZOLE DERIVATIVES Public/Granted day:2019-07-25
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