Invention Grant
- Patent Title: Compositions and methods for epigenome editing
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Application No.: US15549842Application Date: 2016-02-09
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Publication No.: US10676726B2Publication Date: 2020-06-09
- Inventor: Charles A. Gersbach , Isaac Hilton
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2016/017221 WO 20160209
- International Announcement: WO2016/130600 WO 20160818
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N9/10 ; C12N15/11 ; C12N15/63 ; C12N15/85
Abstract:
Disclosed herein are CRISPR/Cas9-based gene activation systems that include a fusion protein of a Cas9 protein and a protein having histone acetyltransferase activity, and methods of using said systems.
Public/Granted literature
- US20180023064A1 COMPOSITIONS AND METHODS FOR EPIGENOME EDITING Public/Granted day:2018-01-25
Information query
