Systems and methods are described for implementation by a computing system having a non-uniform memory access (NUMA) architecture comprising a plurality of NUMA nodes. A query of a document store storing a collection of slices each comprising one or more documents is received from a client. Thereafter, it is determined which of the slices within the document store are required for execution of the query. An execution plan is then generated, using the query, that comprises a plurality of nodes each specifying at least one database operation to execute a portion of the query. The execution plan assigns one of the plurality of NUMA nodes to each slice determined to be required for execution of the query. The database operations specified by the nodes of the execution plan are then executed using the corresponding assigned NUMA nodes for the associated slice. Data responsive to the query is then provided to the client.