Provided are devices and methods for monitoring a physical asset in real-time based on simulated data being transformed and applied to a virtual asset corresponding to the physical asset. In one example, the method includes receiving a data stream acquired from a structure of an asset being monitored, determining an accumulated damage amount to the asset based on the received information, the determining including performing an incremental rainflow counting algorithm on the received data stream from the asset being monitored, stress transfer function evaluations, and damage calculations with S-N curves, and outputting information concerning the accumulated damage amount of the asset for display on a display device.