Disclosed herein is an improved pharmaceutical management system and methods implemented by the system for sorting and identifying a medicine via its label and/or package. The method comprises steps of: (1) receiving a plurality of raw images of a package of a medication; (b) juxtaposing two of the plurality of raw images to produce a combined image, in which the two raw images are different from each other; (c) processing the combined image to produce a reference image; and (d) establishing the medication library with the aid of the reference image. The system comprises an image capturing device, an image processor, and a machine learning processor. The image processor is programmed with instructions to execute the method for producing a combined image.