Invention Grant
- Patent Title: Pharmaceutical composition for preventing or treating DYRK-related diseases, containing pyridine-based compound as active ingredient
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Application No.: US16470014Application Date: 2017-12-15
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Publication No.: US10765669B2Publication Date: 2020-09-08
- Inventor: Sungchan Cho , Miri Choi , Joo Youn Lee
- Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- Applicant Address: KR Daejeon KR Daejeon
- Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY,KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- Current Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY,KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- Current Assignee Address: KR Daejeon KR Daejeon
- Agency: Merchant & Gould P.C.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@46662b0e com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6f853130
- International Application: PCT/KR2017/014893 WO 20171215
- International Announcement: WO2018/111049 WO 20180621
- Main IPC: A61K31/381
- IPC: A61K31/381 ; A61K31/444 ; A23L33/10
Abstract:
The present invention relates to a pharmaceutical composition the prevention or treatment of DYRK-related diseases containing a pyridine-based compound as an active ingredient, a pyridine-based compound of the present invention which is used as an active ingredient of the pharmaceutical composition inhibits the activity of DYRK1A with very high efficacy and selectivity, thereby can be used effectively in the prevention or treatment of DYRK-related diseases, such as Down syndrome, degenerative brain diseases, cancer, and metabolic diseases.
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