Invention Grant
- Patent Title: Online dilution for a liquid chromatography system using a sample metering pump
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Application No.: US16007299Application Date: 2018-06-13
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Publication No.: US10802001B2Publication Date: 2020-10-13
- Inventor: Joshua A. Burnett , John M. Auclair
- Applicant: Waters Technologies Corporation
- Applicant Address: US MA Milford
- Assignee: WATERS TECHNOLOGIES CORPORATION
- Current Assignee: WATERS TECHNOLOGIES CORPORATION
- Current Assignee Address: US MA Milford
- Agency: Schmeiser, Olsen & Watts LLP
- Agent William G. Guerin
- Main IPC: G01N30/20
- IPC: G01N30/20 ; G01N30/06 ; G01N1/38 ; G01N30/34 ; G01N30/02 ; G01N35/10

Abstract:
An apparatus for diluting a sample in a liquid chromatography system includes a metering pump, a sample needle and a sample valve. One of the sample valve ports is in fluid communication with the first pump port, a second one of the sample valve ports is in fluid communication with the second pump port, and a third one of the sample valve ports is in fluid communication with the sample needle. The sample valve can be configured in a first to conduct a solvent to the first pump port and to fluidically terminate the second pump port, and in a second state in which the sample needle is in fluid communication with the second pump port. A merge valve configurable in different states is in fluid communication with the sample valve. The states of the sample valve and merge valve can be controlled to perform online dilution.
Public/Granted literature
- US20180364203A1 ONLINE DILUTION FOR A LIQUID CHROMATOGRAPHY SYSTEM USING A SAMPLE METERING PUMP Public/Granted day:2018-12-20
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