A pixel control circuit and control method, a pixel unit, a display substrate and device are provided. The pixel control circuit includes: a pressure detecting sub-circuit and a switching sub-circuit; the pressure detecting sub-circuit is connected to a control node, and configured to control a potential of the control node to be a first potential when a pressure signal is detected; and the switching sub-circuit is connected to a first power source terminal, a light-emitting sub-circuit in the pixel unit and the control node respectively, and configured to provide a first power source signal from the first power source terminal for the light-emitting sub-circuit when the potential of the control node is the first potential. The pixel control circuit effectively raises the speed of fingerprint detection.