Invention Grant
- Patent Title: Antibody evolution immunogens
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Application No.: US15864822Application Date: 2018-01-08
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Publication No.: US10849970B2Publication Date: 2020-12-01
- Inventor: Barton F. Haynes , Hua-Xin Liao , Rebecca M. Lynch , Tongqing Zhou , Feng Gao , Scott Boyd , George M. Shaw , Beatrice H. Hahn , Thomas B. Kepler , Bette T. Korber , Peter Kwong , John R. Mascola
- Applicant: Duke University , Triad National Security, LLC , The Trustees of The University of Pennsylvania , Trustees of Boston University , The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services , The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US NC Durham US NM Los Alamos US PA Philadelphia US MA Boston US MD Rockville US CA Palo Alto
- Assignee: Duke University,Triad National Security, LLC,The Trustees of The University of Pennsylvania,Trustees of Boston University,The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services,The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: Duke University,Triad National Security, LLC,The Trustees of The University of Pennsylvania,Trustees of Boston University,The Government of The United States of America as Represented by the Secretary of the Department of Health and Human Services,The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US NC Durham US NM Los Alamos US PA Philadelphia US MA Boston US MD Rockville US CA Palo Alto
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: A61K39/21
- IPC: A61K39/21 ; A61K39/12 ; C07K14/005 ; C12N7/00 ; A61K39/00

Abstract:
The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
Public/Granted literature
- US20180360948A1 ANTIBODY EVOLUTION IMMUNOGENS Public/Granted day:2018-12-20
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