Invention Grant
- Patent Title: Treatment of cancer using GFR α-4 chimeric antigen receptor
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Application No.: US15503971Application Date: 2015-08-14
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Publication No.: US10851149B2Publication Date: 2020-12-01
- Inventor: Donald L. Siegel , Michael C. Milone , Vijay Bhoj , Christoph Rader
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , NOVARTIS AG , THE SCRIPPS RESEARCH INSTITUTE
- Applicant Address: US PA Philadelphia CH Basel US CA La Jolla
- Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA,NOVARTIS AG,THE SCRIPPS RESEARCH INSTITUTE
- Current Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA,NOVARTIS AG,THE SCRIPPS RESEARCH INSTITUTE
- Current Assignee Address: US PA Philadelphia CH Basel US CA La Jolla
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle
- International Application: PCT/US2015/045349 WO 20150814
- International Announcement: WO2016/025880 WO 20160218
- Main IPC: C07K14/725
- IPC: C07K14/725 ; C07K14/705 ; C07K16/28 ; C07K16/30 ; C07K14/71 ; A61K39/00 ; A61K38/00

Abstract:
The present invention relates to compositions and methods for treating diseases, disorders or conditions associated with the expression of the Glycosyl-phosphatidylinositol (GPI)-linked GDNF family α-receptor 4 (GFRα4).
Public/Granted literature
- US20170334967A1 TREATMENT OF CANCER USING GFR ALPHA-4 CHIMERIC ANTIGEN RECEPTOR Public/Granted day:2017-11-23
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