Techniques are disclosed for improving navigation accuracy for a mobile platform. In one example, a navigation system comprises an image sensor that generates a plurality of images, each image comprising one or more features. A computation engine executing on one or more processors of the navigation system processes each image of the plurality of images to determine a semantic class of each feature of the one or more features of the image. The computation engine determines, for each feature of the one or more features of each image and based on the semantic class of the feature, whether to include the feature as a constraint in a navigation inference engine. The computation engine generates, based at least on features of the one or more features included as constraints in the navigation inference engine, navigation information. The computation engine outputs the navigation information to improve navigation accuracy for the mobile platform.