Invention Grant
- Patent Title: Method and kit for identifying lupus anticoagulant (LA) associated with antiphospholipid syndrome
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Application No.: US15491152Application Date: 2017-04-19
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Publication No.: US10935560B2Publication Date: 2021-03-02
- Inventor: Ralph E. Bottenus , Zhenghua Cao
- Applicant: Instrumentation Laboratory Company
- Applicant Address: US MA Bedford
- Assignee: Instrumentation Laboratory Company
- Current Assignee: Instrumentation Laboratory Company
- Current Assignee Address: US MA Bedford
- Agency: Burns & Levinson, LLP
- Agent Janine M. Susan
- Main IPC: G01N33/86
- IPC: G01N33/86 ; C12Q1/56 ; G01N33/564
Abstract:
The invention described herein relates to a method and kit for the diagnosis of antiphospholipid syndrome in patients, wherein a coagulation inhibitor and normal pooled plasma mixture reduce the factor deficiency effect of patient plasma, and coagulation inhibitor interference in patient plasma, and increases specificity and the sensitivity for detecting lupus anticoagulants in the patient's blood in a phospholipid-dependent clotting assay.
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Information query
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