Invention Grant
- Patent Title: On-demand rapid synthesis of lomustine under continuous flow conditions
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Application No.: US16654103Application Date: 2019-10-16
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Publication No.: US10941111B2Publication Date: 2021-03-09
- Inventor: David H Thompson , Robert Graham Cooks , Christina Ramires Ferreira , Zinia Jaman
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: D'Hue Law LLC
- Agent Cedric A. D'Hue
- Main IPC: C07C273/18
- IPC: C07C273/18 ; B01J19/00 ; C07C275/68

Abstract:
Disclosed herein is a continuous manufacturing process for lomustine that has a short residence time and 63 percent yield. Major advantages of this process are that the total production cost for lomustine is lower, the product is higher quality, and the manufacturing operation is safer for production personnel.
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