A signal processing circuit for processing a sensing signal from a sensor includes an amplifier, an input capacitor group, a compensation capacitor group and first/second switch groups. The amplifier, coupled to a first floating node and a second floating node, is configured to amplify the sensing signal coupled from the first floating node and the second floating node. The first switch group is coupled between a first node group and the first and second floating nodes. The second switch group is coupled between a second node group and the first node group. The input capacitor group is coupled to the second node group and an input node group, and configured to receive the sensing signal coupled from the input node group. The compensation capacitor group is coupled between a compensation node group and the second node group, and configured to receive a compensation signal coupled from the compensation node group.