Invention Grant
- Patent Title: BK channel-modulating peptides and their use
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Application No.: US16222534Application Date: 2018-12-17
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Publication No.: US11214595B2Publication Date: 2022-01-04
- Inventor: Luisa Lynn Scott , Joseph Paul Walton
- Applicant: UNIVERSITY OF SOUTH FLORIDA , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US FL Tampa; US TX Austin
- Assignee: UNIVERSITY OF SOUTH FLORIDA,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: UNIVERSITY OF SOUTH FLORIDA,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US FL Tampa; US TX Austin
- Agency: Quarles & Brady LLP
- Main IPC: C07K7/54
- IPC: C07K7/54 ; A61K38/12 ; A61K38/08 ; A61K47/64 ; A61P43/00 ; A61P27/16 ; C07K7/06 ; A61K38/00
Abstract:
The present invention concerns peptides and nucleic acids encoding the peptides, and their use for modulating large conductance Ca2+ activated K+ (BK) channel activity in cells; for treating conditions such as presbycusis (age-related hearing loss), audiogenic seizures, alcohol addiction, cancer, and neurodegenerative disease; and for delivering a cargo moiety to the brain of a subject through the blood-brain barrier.
Public/Granted literature
- US20190112339A1 BK CHANNEL-MODULATING PEPTIDES AND THEIR USE Public/Granted day:2019-04-18
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