公开(公告)号：US20250160736A1

公开(公告)日：2025-05-22

申请号：US18954450

申请日：2024-11-20

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Shaun CANAVAN ,  Md Taufeeq UDDIN ,  Ghadh ALZAMZMI

IPC: A61B5/00

Abstract: Technology for cooperative learning pain assessment may include a sensed pain classifier to determine a sensed context and a pain assessment classifier to determine an inferred pain score. Disclosed technology may determine an uncertainty score based on the sensed context and the inferred pain score. Responsive to the uncertainty score meeting a first threshold condition, a manual label for the subject data may be used to update the sensed pain classifier or the pain assessment classifier. Responsive to the uncertainty score meeting a second threshold condition, a generated label for the subject data may be used to update the sensed pain classifier or the pain assessment classifier. The inferred pain score may be provided as an assessed pain result for the subject.

公开(公告)号：US20250113809A1

公开(公告)日：2025-04-10

申请号：US18779510

申请日：2024-07-22

Applicant: University of South Florida

Inventor： Lianchun Wang

IPC: A01K67/0276 ,  C12N9/10 ,  C12N9/22 ,  C12N15/11 ,  C12N15/90

Abstract: The present disclosure relates to heparan sulfate transgenic models and methods of use thereof.

公开(公告)号：US12229959B2

公开(公告)日：2025-02-18

申请号：US17971295

申请日：2022-10-21

Applicant: UNIVERSITY OF SOUTH FLORIDA ,  STEREOLOGY RESOURCE CENTER, INC.

Inventor： Palak Pankajbhai Dave ,  Dmitry Goldgof ,  Lawrence O. Hall ,  Peter R. Mouton

IPC: G06T7/00 ,  G06N3/08 ,  G06N20/00 ,  G06T5/20 ,  G06T5/70 ,  G06T7/11 ,  G06T7/174 ,  G06T17/20 ,  G06V20/69

Abstract: Systems and methods for automated stereology using deep learning are disclosed. The systems include an update in the form of a semi-automatic approach for ground truth preparation in 3D stacks of microscopy images (disector stacks) for generating more training data. The systems also present an exemplary disector-based MIMO framework where all the planes of a 3D disector stack are analyzed as opposed to a single focus-stacked image (EDF image) per stack. The MIMO approach avoids the costly computations of 3D deep learning-based methods by using the 3D context of cells in disector stacks; and prevents stereological bias in the previous EDF-based method due to counting profiles rather than cells and under-counting overlap-ping/occluded cells. Taken together, these improvements support the view that AI-based automatic deep learning methods can accelerate the efficiency of unbiased stereology cell counts without a loss of accuracy or precision as compared to conventional manual stereology.

公开(公告)号：US20250051208A1

公开(公告)日：2025-02-13

申请号：US18710601

申请日：2022-11-16

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Daniel H. YEH ,  Itzé Alejandra KENNEY ,  Cynthia J CASTRO ,  Hsiang-Yang SHYU ,  Ahmet Erkan UMAN

IPC: C02F9/00 ,  B01D61/14 ,  B01D61/16 ,  B01D61/18 ,  B01D63/06 ,  B01D69/02 ,  B01D71/34 ,  C02F1/00 ,  C02F1/28 ,  C02F1/44 ,  C02F1/52 ,  C02F3/28

Abstract: Provided is a solid precipitation reactor useful for waste-water treatment. The reactor can include a reaction chamber configured to receive feedwater and to allow particulates to at least partially precipitate from the feedwater to form an effluent, and a membrane module having at least one membrane filter configured to receive effluent from the reaction chamber and to filter suspended particulates from the effluent to produce a permeate and a concentrate. The concentrate can be reintroduced to the re-action chamber to allow additional particulates to precipitate. Systems and methods for wastewater treatment, and methods for regenerating a zeolite cation exchanger, using the solid precipitation reactor are also provided.

公开(公告)号：US20250049338A1

公开(公告)日：2025-02-13

申请号：US18719461

申请日：2022-12-12

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： ASHWIN PARTHASARATHY ,  ABDUL MOHAIMEN SAFI

IPC: A61B5/026 ,  A61B5/00 ,  G06T7/00 ,  G06T7/20

Abstract: A SyntheticMulti-Exposure Speckle Imaging (syMESI) methodology necessarily utilizing an optical interferometer apparatus as part of the speckle imaging system to overcome the optical detector noise that conventionally limits the reliable and accurate determination of a speckle contrast characteristic at low exposure times. The use of such methodology enabled a quantitative determination of absolute value(s) of changes of motion at the target object (such as blood flow changes in tissue) at low photon budget of less than 40 counts of average detection intensity and/or quantitative imaging of the blood flow at the object in interoperative setting with a low-cost camera sensor.

公开(公告)号：US20250028812A1

公开(公告)日：2025-01-23

申请号：US18713166

申请日：2022-11-23

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Yunghsiao CHUNG ,  Feng YU ,  Stephen Edward SADDOW ,  Junjie XIONG

IPC: G06F21/44

Abstract: A method and a system for identifying authenticity of an electronic component is disclosed. The method may include obtaining chip data of an electronic component: extracting feature information of the chip data for reducing noise of the chip data: providing the feature information of the chip data to a trained deep learning model; and providing a user with an authenticity indication for the electronic component based on an output of the deep learning model. Other aspects, embodiments, and features are also claimed and described.

公开(公告)号：US20250009734A1

公开(公告)日：2025-01-09

申请号：US18757228

申请日：2024-06-27

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Ying Yang

IPC: A61K31/47

Abstract: Disclosed are methods for treating congenital lymphedema or increasing lymphatic valve growth by administering a FOXO1 inhibitor. Also disclosed are methods for increasing nuclear β-catenin activity in a cell by contacting the cell with a FOXO1 inhibitor.

公开(公告)号：US12177631B2

公开(公告)日：2024-12-24

申请号：US18301536

申请日：2023-04-17

Applicant: University of South Florida

Inventor： David Eddins ,  Joseph Walton

IPC: H04R25/00

Abstract: A device and method that supplements sensory input, thereby providing a supplemented sensory environment, to induce plasticity within the central nervous system that effectively overcomes sensory-neural processing deficits or strengthens specific sensory-neural abilities. In one implementation, ear-level hearing devices are used to deliver therapeutic sound with specific acoustic features that serve as archetypes of stimulus features for which sensory-neural processing is compromised by a sensory-neural deficit.

公开(公告)号：US12173544B2

公开(公告)日：2024-12-24

申请号：US17571249

申请日：2022-01-07

Applicant: University of South Florida

Inventor： Kyle Brandon Reed

IPC: E05F11/54 ,  E05B1/00 ,  E05F13/02

Abstract: A door opener for a door includes a frame coupled to the door and a wheel rotatably supported by the frame. The wheel, including its position relative to the door and frame, as well as its shape, are configured to convert a downward force applied by a user's foot into a lateral force that opens the door by rotating the wheel in contact with the floor.

公开(公告)号：US12171779B2

公开(公告)日：2024-12-24

申请号：US18077533

申请日：2022-12-08

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Nurettin Sahiner ,  Ramesh Ayyala

IPC: A61K31/737 ,  A61K9/00 ,  A61K9/50

Abstract: Disclosed herein are crosslinked chondroitin sulfate particles crosslinked chondroitin sulfate particle polyelectrolytes. The particles are useful in drug delivery applications. The particles may be used to treat various conditions, including bacterial and fungal infections.