Invention Grant
- Patent Title: Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform
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Application No.: US16090561Application Date: 2017-03-31
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Publication No.: US11246924B2Publication Date: 2022-02-15
- Inventor: Joel H. Collier , Yaoying Wu , Vincent P. Conticello
- Applicant: Duke University , Emory University
- Applicant Address: US NC Durham; US GA Atlanta
- Assignee: Duke University,Emory University
- Current Assignee: Duke University,Emory University
- Current Assignee Address: US NC Durham; US GA Atlanta
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2017/025596 WO 20170331
- International Announcement: WO2017/173398 WO 20171005
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K39/00 ; A61K39/385 ; A61K47/64 ; A61K38/05 ; A61K39/39 ; C07K14/71
Abstract:
Embodiments are directed to fibrillar adjuvants. Epitopes assembled into nanofibers by a short synthetic fibrillization domain elicited high antibody titers in the absence of any adjuvant.
Information query
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