A process for manufacture of a profiled non-stick pan with a concave-convex pattern, which includes the following steps: preparing a flat blank for forming a pan body; screen printing a layer of ink with a predetermined pattern on a surface of the blank for a pan body, then drying and curing the ink; etching, by an etching process, the surface of the blank, on areas of the surface not covered by the ink, then cleaning and drying the blank, and retaining the ink; spraying non-stick pan coating on the blank, then baking the blank at high temperature, to enable the ink to automatically peel off at high temperature; pressing and stretching the blank to form a profiled pan body, then deburring and polishing on an edge of the pan body.