Invention Grant
- Patent Title: Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules
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Application No.: US16745182Application Date: 2020-01-16
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Publication No.: US11300562B2Publication Date: 2022-04-12
- Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Quarles & Brady, LLP
- Main IPC: B01J19/08
- IPC: B01J19/08 ; G01N33/50 ; C12Q1/6876 ; G01N1/28 ; G01N33/487 ; G01N33/68 ; H05H1/24 ; H01J49/00

Abstract:
This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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