The present disclosure is directed to systems and methods of selectively implementing SCA mitigation elements on a per-thread basis to mitigate the effects of side channel attacks. Processor core circuits initiate a plurality of processor threads. Each of a plurality of SCA mitigation features include one or more SCA mitigation elements. SCA mitigation control circuitry associates a register circuit with each respective one of the plurality of processor threads initiated by the processor core circuits. The SCA mitigation control circuitry selectively ENABLES/DISABLES one or more SCA mitigation elements for each of the plurality of processor threads. The ENABLEMENT/DISABLEMENT of each of the SCA mitigation elements may be autonomously adjusted by the SCA mitigation control circuitry and/or manually adjusted via one or more user inputs provided to the SCA mitigation control circuitry.