A method for operating a radio frequency communications system includes, while operating a first radio frequency communications device in a calibration mode, for each setting of a plurality of settings of a programmable gain amplifier in a receiver of the first radio frequency communications device configured in a zero-intermediate frequency mode of operation, generating an estimate of a DC offset in each of a plurality of digital samples received from an analog circuit path including the programmable gain amplifier, and storing in a corresponding storage element, a compensation value based on the estimate.