Invention Grant
- Patent Title: Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
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Application No.: US15749797Application Date: 2016-08-04
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Publication No.: US11458205B2Publication Date: 2022-10-04
- Inventor: Ashutosh Chilkoti , Samagya Banskota , Parisa Yousefpour , Jayanta Bhattacharyya
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2016/045655 WO 20160804
- International Announcement: WO2017/024182 WO 20170209
- Main IPC: A61K47/64
- IPC: A61K47/64 ; A61K39/395 ; A61K39/00 ; C07K7/06 ; A61P35/00 ; A61K38/00 ; A61K47/60 ; A61K47/10 ; C12N15/70 ; A61K31/337
Abstract:
Provided herein are conjugates including a polypeptide and one or more drug molecules. The polypeptide includes one or more charged motifs, and may further include one or more uncharged motifs. The conjugates may be used to effectively deliver the drug molecule to a subject.
Public/Granted literature
- US20180228908A1 GENETICALLY ENCODED INTRINSICALLY DISORDERED STEALTH POLYMERS FOR DELIVERY AND METHODS OF USING SAME Public/Granted day:2018-08-16
Information query
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