Invention Grant
- Patent Title: High specific activity preparation of F-18 tetrafluoroborate
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Application No.: US16095865Application Date: 2017-04-24
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Publication No.: US11532406B2Publication Date: 2022-12-20
- Inventor: Timothy R. DeGrado , Huailei Jiang
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Quarles & Brady LLP
- International Application: PCT/US2017/029089 WO 20170424
- International Announcement: WO2017/189415 WO 20171102
- Main IPC: A61K51/02
- IPC: A61K51/02 ; C01B35/06 ; G21G4/08 ; B01J41/05
Abstract:
Embodiments of the invention provide methods of synthesizing 18F-tetrafluoroborate (18F-TFB) via direct radiofluorination on boron trifluoride (BF3) to enhance both labeling yield and specific activity. Uses of 18F-TFB are also contemplated.
Public/Granted literature
- US20210225547A1 HIGH SPECIFIC ACTIVITY PREPARATION OF F-18 TETRAFLUOROBORATE Public/Granted day:2021-07-22
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