Video stream data is selectively scaled so that sections within regions of interest (ROI) maintain high resolution while areas not within the region of interest are down-scaled to reduce bandwidth cost of transmission. A low compression encoder compresses sections of a video frame corresponding to one or more ROI without motion search or prediction mode decision to generate low-compression section data. The video frame is downscaled and a high compression encoder compresses the resulting downscaled video frame with prediction mode decision to generate high-compression frame data.