Invention Grant
- Patent Title: Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
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Application No.: US16614282Application Date: 2018-05-15
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Publication No.: US11554097B2Publication Date: 2023-01-17
- Inventor: Ashutosh Chilkoti , Kelli Luginbuhl , Davoud Mozhdehi
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2018/032785 WO 20180515
- International Announcement: WO2018/213320 WO 20181122
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/127 ; A61K9/107 ; A61K31/337 ; A61K31/704 ; A61K47/42 ; A61K38/02

Abstract:
Disclosed herein are conjugates including a fatty acid, a self-assembly domain, and a polypeptide having phase transition behavior. Further disclosed are methods of using the conjugates to treat disease, methods of delivering an agent, and methods of preparing the conjugates.
Public/Granted literature
- US20210154143A1 RECOMBINANT PRODUCTION OF HYBRID LIPID-BIOPOLYMER MATERIALS THAT SELF-ASSEMBLE AND ENCAPSULATE AGENTS Public/Granted day:2021-05-27
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