Invention Grant
- Patent Title: Hyperbranched polymers and polyplexes and DNA or RNA delivery systems including the same
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Application No.: US15720542Application Date: 2017-09-29
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Publication No.: US11590234B2Publication Date: 2023-02-28
- Inventor: Peter X. Ma , Xiaojin Zhang
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Dierker & Kavanaugh, P.C.
- Main IPC: A61K47/00
- IPC: A61K47/00 ; A61K47/50 ; A61K47/59 ; C08G83/00 ; C08G73/02 ; C08F210/02 ; C08G63/66 ; A61K47/69 ; A61K47/60 ; A61L27/18 ; A61L27/26 ; A61L27/44 ; A61L27/52 ; A61L27/54 ; A61L27/56 ; A61L27/58 ; C08G81/00 ; C12N15/113
Abstract:
A hyperbranched polymer includes a hyperbranched, hydrophobic molecular core, respective low molecular weight polyethyleneimine chains attached to at least three branches of the hyperbranched, hydrophobic molecular core, and respective polyethylene glycol chains attached to at least two other branches of the hyperbranched, hydrophobic molecular core. Examples of the hyperbranched polymer may be used to form hyperbranched polyplexes, and may be included in DNA or RNA delivery systems.
Public/Granted literature
- US20180021441A1 HYPERBRANCHED POLYMERS AND POLYPLEXES AND DNA OR RNA DELIVERY SYSTEMS INCLUDING THE SAME Public/Granted day:2018-01-25
Information query
