Invention Grant
- Patent Title: Engineered influenza polynucleotides, viruses, vaccines and methods of making and using the same
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Application No.: US16317427Application Date: 2017-07-12
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Publication No.: US11596683B2Publication Date: 2023-03-07
- Inventor: Nicholas Scott Heaton , Alfred Theodore Harding , Brook Elizabeth Heaton
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Quarles & Brady LLP
- International Application: PCT/US2017/041737 WO 20170712
- International Announcement: WO2018/013704 WO 20180118
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K39/145 ; A61P31/16 ; C07K14/11 ; C07K14/005 ; C07K14/00 ; A61K39/12 ; C12N7/00 ; C12N15/86 ; A61K39/39 ; C12N9/24 ; A61K39/00
Abstract:
Engineered Influenza polynucleotides, viruses, vaccines, and methods of making and using the same are provided. More specifically, the present inventors have developed replication competent engineered influenza viruses having, for example, a modified segment 4 and/or segment 6 that include at least one additional polynucleotide encoding a heterologous polypeptide.
Public/Granted literature
- US20190224305A1 ENGINEERED INFLUENZA POLYNUCLEOTIDES, VIRUSES, VACCINES AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2019-07-25
Information query
