Invention Grant
- Patent Title: In vitro and in vivo enrichment strategy targeting lymphocytes derived from vector transduced HSCs for therapy of disorders
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Application No.: US16619883Application Date: 2018-06-06
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Publication No.: US11597917B2Publication Date: 2023-03-07
- Inventor: Jeffrey A. Medin , John F. Dipersio , Murtaza S. Nagree
- Applicant: THE MEDICAL COLLEGE OF WISCONSIN, INC. , UNIVERSITY HEALTH NETWORK , WASHINGTON UNIVERSITY IN ST. LOUIS
- Applicant Address: US WI Milwaukee; CA Toronto; US MO St. Louis
- Assignee: THE MEDICAL COLLEGE OF WISCONSIN, INC.,UNIVERSITY HEALTH NETWORK,WASHINGTON UNIVERSITY IN ST. LOUIS
- Current Assignee: THE MEDICAL COLLEGE OF WISCONSIN, INC.,UNIVERSITY HEALTH NETWORK,WASHINGTON UNIVERSITY IN ST. LOUIS
- Current Assignee Address: US WI Milwaukee; CA Toronto; US MO St. Louis
- Agency: Quarles & Brady LLP
- International Application: PCT/US2018/036292 WO 20180606
- International Announcement: WO2019/009979 WO 20190110
- Main IPC: C12N9/04
- IPC: C12N9/04 ; A61P43/00 ; A61K9/00 ; A61K35/28 ; C12N5/0789 ; C12N7/00 ; C12N9/40 ; C12N9/24 ; C12N9/80 ; C12N15/86
Abstract:
The present invention is related to a dual promoter lentiviral vector and methods of use for the treatment of diseases and disorders, specifically lysosomal storage disorders.
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